Discipline of Virology

Current Research

Project Title: Aptamer Conjugated Hybrid Nanoparticles for Targetted Delivery Of An Antiretroviral Drug To The Lymph Nodes

Collaborators: Prof Thirumala Govender

Funding: UKZN Nanotechnology Platform


Project Title: Impact of HIV, Antiretroviral Therapy and TB Genotype on Survival in MDR and XDR TB in a HIV positive adult South African cohort.

Collaborators: Neel Gandhi and his team from Emory University School of Medicine, and KolekaMlisana.

Funding: NIH (non-IND study)


Project Title: KwaZulu-Natal HIV Drug Resistance Surveillance Study.

Collaborators: Yunus Moosa (University of KwaZulu-Natal), South Africa; Vincent Marconi and his team from Emory University School of Medicine, Atlanta, Georgia, USA; Daniel Kuritzkes (Harvard University School of Medicine, Boston, Massachusetts, USA); with researchers from University of Colorado, Denver, and Centers for Disease Control, Atlanta, Georgia, USA

Funding: The National Institute of Allergy and Infectious Diseases (non-IND study)


Project Title: Zidovudine (AZT) resistance in pregnant patients enrolled in the dual therapy arm of the PMTCT program

Principal Investigator: Reshmi Samuel

Collaborators: Roger Paredes (IrsiCaixaRetrovirology Laboratory, Barcelona, Spain) and Michelle Gordan (HPP, UKZN)

Funding: NHLSRT and MRC


Project Title: Assessment of several synthetic peptides for anti-HIV activity

Collaborators: Gert Kruger

Funding: India-Brazil-South Africa Trilateral Cooperation in Science & Technology, NRF, K-RITH, MRC.  Sample testing on-going.Four papers published and four being drafted.


Project Title: Inhibition of HIV-1 Encapsidation by Targeted Poly-ribonucleotide Decoys: A Novel Nanoparticle Approach

Principal Investigators: RaveenParboosing

Collaborator: Gert Kruger.

Funding: Discovery Foundation and NRF


Project Title: Association between clinical correlates and CMV viral load

Researchers: Department of Paediatrics, UKZN, Kerusha Govender

Funding: Discovery Foundation, NHLS Research Trust


Project Title: Prevalence of HBV infection in infants in KZN, South Africa

Researchers: Nokukhanya Msomi – Virology MMed       

Funding: NHLS Research Trust 


Project Title:  To evaluate the end point  of Herpes Simplex Virus in cell culture using TCID50 and comparing it to real time qualitative PCR.

Researchers:  Subitha Govender, BSC Hons, Dr Pravi Moodley

Funding:  UKZN, College of Health Sciences


Project Title:  Validation of a two-spot method of dried blood spot specimen processing prior to HIV polymerase chain reaction

Researchers: Dr Kerusha Govender- Virology MMed

Funding:  Virology, KZN


Project Title:  HIV-associated Hepatic Tuberculosis in South Africa

Researchers:  Lilishia Gounder Virology MMed, Pravikrishnen Moodley

Collaborator: Paul K. Drain- Division of Infectious Diseases, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA, Andrew J. Hickey-University of Maryland School of Medicine, Baltimore, USA, Mahomed-Yunus S. Moosa -Department of Infectious Diseases, Nelson R. Mandela School of Medicine

Funding:  Department of Infectious Diseases, UKZN


Project Title:  Anaemia and pure cell aplasia secondary to Parvovirus in HIV-infected and un-infected patients

Researchers: Dr Kerri-Lee Ann Francois- Virology MMed

Funding:  Virology, KZN


Project Title:  Pattern of viral respiratory infection in children less than 5 years in KZN, South Africa

Researchers: Dr Tayo Famoroti- Virology MMed

Funding:  Virology, KZN


Project Title:  Occupational exposures to blood borne viral infections with relevance to HIV Hepatitis B and Hepatitis C in KZN

Researchers:  Dr Tinyiko Khosa– Virology MMed

Funding:  Virology, KZN


Project Title: Prevalence of Delta Hepatitis Infection in KwaZulu-Natal Province, South Africa     

Researchers: Dr Raveen Parboosing, Virology, UKZN   

Funding: NHLS Research Trust

End Date: December 2014


Project Title: JC Virus in Neurological Patients Infected with HIV            

Researchers:  Dr Pravi Moodley, Lavanya Singh Virology, UKZN, Neurology, UKZN       

Funding: NHLS Research Trust

End Date: December 2015